If you are on MacOS, unplug and replug. This is typical of an improperly shut down connection to it, because of an incompatibility between libusb and the FT601 USB chip. There is a discussion a few weeks ago on this group that I started about how to patch libusb to fix it.
had to dig back and find it. here is the discussion:
the patch is do-it-yourself with an editor, since it is just a single line to comment out of the source code. This was with libusb 1.0.22 source. After rebuilding libusb, make sure you get LimeSuite to use the updated version.