Hey @Zack, isn’t the inability to reproduce almost expected nowadays? You didn’t really think this was foolproof, right? 
I am a human fuzzer (or fool). 
Some specifics:
- USB3 (which I don’t have problems with using USB-powered HDD)
- Linux 4.11.3
- LimeSuite from github (as recommended by you (and thanks))
- libusb 1.0.21
The application software doesn’t seem to be an issue (I consider LimeSuite as a config tool and not an app)
I have used Gqrx, gnuradio, URH, SDRAngel, CubicSDR and others.
I have not used my LimeSDR in some time now but will be happy to try things out if you have any ideas. But since you tried to repro I am not sure what could be tried.
In the other post * there is mention of missing firm/gate/ware in ~/.local/share/LimeSuite/images
Could that be a source of problems here?
@JTAG mentions that it happens every 2nd time. I can’t recall if that’s true for me but it might be. Could that provide a clue? Perhaps some arbitration issue?
i.e. an app shuts down but doesn’t release the device properly, the next app comes along and wants device control but can’t get it, so it does some kind of reset and that reset does the wrong thing or the board does the wrong thing because of unclean device release?
Maybe this is a libusb problem and not a USB hardware problem?