Issues with using LimeSDR in MIMO2x2 Spatial Multiplexing Mode

I have the same problem. Check this thread. RX channels alignment

The disabling clock routine did not work for me. Also the shift seems to be random ±2samples with subsample (1/4th if remember correctly) steps. Give update if it did the job in your case.
PS
Subsample shift may seem odd but in lms7002d we have to do with sigma delta adc operating at higher frequency than output.